Prevention of systolic anterior motion after mitral valve repair with an anterior leaflet valvuloplasty.
Published in The Journal of heart valve disease
Quantitative Accuracy of Penalized-Likelihood Reconstruction for ROI Activity Estimation.
Published in IEEE Transactions on Nuclear Science
Estimation of the tracer uptake in a region of interest (ROI) is an important task in emission tomography. ROI quantification is essential for measuring clinical factors such as tumor activity, growth rate, and the efficacy of therapeutic interventions. Accuracy of ROI quantification is significantly affected by image reconstruction algorithms. In ...
Crystal identification in positron emission tomography using nonrigid registration to a Fourier-based template.
Published in Physics in Medicine and Biology
Modern positron emission tomography (PET) detectors are typically made from 2D modular arrays of scintillation crystals. Their characteristic flood field response (or flood histogram) must be segmented in order to correctly determine the crystal of annihilation photon interaction in the system. Crystal identification information thus generated is a...
Dosimetry and adequacy of CT-based attenuation correction for pediatric PET: phantom study.
Published in Radiology
Hypertrophic cardiomyopathy: a real risk factor for stroke.
Published in Scottish Medical Journal
Hypertrophic cardiomyopathy is a common and complex heterogeneous cardiovascular entity. Its relationship to ischaemic stroke and atrial fibrillation is under-recognized and consequently, many patients who should be on oral anticoagulation for stroke prevention go untreated.
A clinical evaluation of the quantitative accuracy of simultaneous emission/transmission scanning in whole-body positron...
Published in European Journal of Nuclear Medicine
We present a clinical evaluation of the quantitative bias which is introduced during simultaneous emission/transmission (SET) acquisition for the application of whole-body positron emission tomography (PET) with fluorine-18 2-fluoro-2-deoxy-d-glucose. The quantitative accuracy of the SET technique was assessed by means of a clinical study involving...
Performance and limitations of positron emission tomography (PET) scanners for imaging very low activity sources.
Published in Physica Medica
Emerging applications for positron emission tomography (PET) may require the ability to image very low activity source distributions in the body. The performance of clinical PET scanners in the regime where activity in the field of view is <1 MBq has not previously been explored. In this study, we compared the counting rate performance of two clini...
Excitation spectroscopy in multispectral optical fluorescence tomography: methodology, feasibility and computer simulati...
Published in Physics in Medicine and Biology
Molecular probes used for in vivo optical fluorescence tomography (OFT) studies in small animals are typically chosen such that their emission spectra lie in the 680-850 nm wavelength range. This is because tissue attenuation in this spectral band is relatively low, allowing optical photons even from deep sites in tissue to reach the animal surface...
Experimental procedure for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (M...
Published in Physics in Medicine and Biology
A simple methodology for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry is presented to enable individuals to undertake such work in a routine clinical environment. Samples of PAG were irradiated using a linear accelerator and imaged using a 0.5 T (22 MHz) Philips Gyroscan MRI sc...
Two in one: a variant of the Stener lesion.
Published in Injury
